IMRT

Local Control of a Quadratic Overdose Penalty

red / yellow voxels: highest contribution to the cost fuction (CF) , i.e. in these voxels the CF puts most ‘pressure’ to the optimizer to reduce dose

example: quadratic overdose penalty for D 0 i.e. area of control only at doses > 25 Gy =25Gy,

25 Gy

Dummy volume around target for gradient

ESTRO IMRT course 2015 IMRT optimization: algorithms&cost functions Brussels October 5th, 2015

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