IMRT

The next step: more than one re-optimization, dose accumulation, probabilistic planning M. Birkner et al. 2003: Adapting inverse planning to patient and organ geometrical variation: algorithm and implementation. Med. Phys. 30(10)

one feedback loop

planning CT

…

…

Fx 1

IMRT plan

Fx 5

Fx 6

Fx N

new plan

1 cm margin around CTV

probabilistic IMRT plan

…

optimizes the expected dose-per-voxel

CT

CT

deformable registration, dose warping, dose accumulation

model motion of each voxel, this enables calculation of average ‘expected’ dose-per-voxel

ESTRO IMRT course 2015 Adaptive Radiotherapy Brussels October 8th, 2015

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