IMRT

Clinical data (1)

Most organs have several radiation complications.

Lung: radiation pneumonitis, fibrosis, functional measures Brainstem: necrosis, neuropathy, radiological changes Complications may have different degrees of severity; as an example lung toxicity can be graded from 1 cough to 5 death. The dosimetric predictors and NTCP parameter sets can vary according to the grade of toxicity which the clinical data refer to.

Ideal system: complete

to record any score

reproducible

inter/intra-observer variability low

sensitive

able to detect changes in treatment intensity