IMRT

RECTUM: late rectal bleeding: DVH + clinical risk factors

LKB

TD50 (Gy) 81 (75-90)

m

n

Observed

0.14 (0.11- 0.19) 0.14 (0.11- 0.19)

0.13 (0.04- 0.25) 0.11 (0.02- 0.23)

w/o previous abd. surgery with previous abd. surgery

85 (78-96)

78 (72-89)

Including clinical risk factor: lower tolerance to radiation (also for fecal incontinence)

Peeters et al, IJROBP, 2006