IMRT

What is the best measure of xerostomia? • Does the tolerance dose of parotid glands differ between subjective measures, objective measures and patient reported outcomes of xerostomia? (data from the first multicenter randomized study of IMRT and conventional RT)

• Patient reported outcomes results are associated with a higher tolerance dose (D50= 33 Gy)

• LENT-SOMA subjective xerostomia is the most useful clinical measure of salivary function (easily measured and strongly associated with the dose-response of the parotid glands)

Miah et al , 2013