IMRT

Validation of QUANTEC guidelines for xerostomia • Lee F et al , R&O, 2013 • 238 pts, EORTG QoL questionnaires • Validation of LKB parameters, • Beetz I et al, Acta Oncologica, 2014 • 307 pts, chemoradio, 3D CRT (56%), IMRT (44%) • Significanly lower rates of xerostomia in pts treated according to guidelines , but the criteria do not completely protect aganist xerostomia • Moiseenko et al , IJROBP 2012 • 66 pts,, flow measurements, gr 4 xerostomia; @3 mths, flow decreases to <25% than pretreatment • Clinical use of the ”20 Gy spared-gland rule” is justified