IMRT

Changes in anatomy over the course of treatment

• 10 H&N pts, IMRT • CTVs and OARs delineated on CBCT at the10 th , 15 th , 20 th , 25 th treatment session and then compared with the planning CT • A statistically significant increase of larynx volume at the 20 th and 25 th CBCT was observed • The main benefit of replanning could be to preserve parotis, not to reevaluate the target

• Check point at the 3 rd week of radiotherapy in this pts cohort (Cozzolino et al , 2014)