Image-Guided Radiotherapy and Chemotherapy in Gynaecological Cancer

IMRT versus 3D-CRT

Dosimetric comparison: meta-analysis

• 13 papers, 222 IMRT and 233 3D-CRT treated patients

• With IMRT better sparing of high dose volumes of bowel and rectum

• No clear gain for bladder and bone marrow

Yang 2012

OAR 25 Gy

30 Gy

35 Gy

40 Gy

45 Gy

Rectum no

- 26.4% - 27.0% - 37.3% -39.5%

Bowel

no

no

no

-17.8% -17.3%

Bladder

no

no

no

no

no