Imaging for Physicists

Selective mediastinal irradiation

• The high negative predictive value of PET for mediastinal lymph nodes, can be exploited by irradiating only PET-positive areas • Selective mediastinal node irradiation results in low isolated nodal failure rates

De Ruysscher et al. 2005; Int. J. Radiat. Oncol. Biol. Phys. 62:998-994