Imaging for early stage breast cancer

Biology and caveats -predisposing factors for late effects

PATIENT-RELATED PROBLEMS Age (e.g. heart disease) Other diseases e.g. rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis, systemic sclerosis Surgical complications Influence from systemic therapy and the timing between RT and systemic therapy

TECHNIQUE-RELATED PROBLEMS Dose, fractionation, hot spots, volume, fotons versus electrons, overall treatment time Future dream: National (or international) doseplan databanks

Future dream: National (or international) clinical databanks ENDPOINT-RELATED PROBLEMS Scoring of late morbidity is subjective, e.g. what is a grade 2 fibrosis? Different scoring systems are used in different studies Future dream: We all use the same scoring system, take photos in a standardised way, evaluate the same endpoints and use the same cutpoints