Imaging for early stage breast cancer

Severe Fibrosis (α/β = 1.9 Gy)

Fibrosis causes breast retraction & nipple displacement

FACT: ✓

In average:

1 Gy increase in dose leads to 1 mm extra retraction of breast contour and nipple position BUT: In dose range betwen <50 Gy these changes are very limited !

University Hospital Erlangen

Cosmetic evaluation of breast conserving treatment for mammary cancer. 2. A quantitative analysis of the influence of radiation dose, fractionation schedules and surgical treatment techniques on cosmetic results. Van Limbergen E et al. Radiother Oncol. ( 1989 )