Imaging for early stage breast cancer

Less local treatment: where is the limit?

N = 1135

Invasive; < 20 mm; N0; G1 or good prognosis subtype

2x2 clinical trial of factorial design:

+/- radiotherapy &

•

+/- tamoxifen

•

Trial entry was allowed to either comparison or both.

Blamey RW, et al. Eur J Cancer. 2013;49:2294-302.