Imaging for early stage breast cancer

Dosimetrical pros & cons for intracavitary applicators

Pros no geographical miss – tissue conformance?

greater dosimetric flexibility with multilumen (ML) applicators dose to skin-rib/chest wall can be reduced with ML applicators non-spherical target volume and high dose modulation with SAVI steep dose gradient at PTV edges with SAVI Cons only spherical target volume with classic Mammosite sphere-like PTV and dose distribution with ML applicators limited dose modulation potential with ML applicators small dose gradient at PTV edges