Imaging for early stage breast cancer

Techniques, change in seroma after surgery

Results: Average intermarker distance (AiMD) between fiducial markers was strongly correlated to seroma volume At simulation median seroma vol was 35.3 cc, and median AiMD was 3.35 cm From simulation the average reduction in AiMD was 10.8% (range 0-36%) to beginning of RT (mean 10 days) and 19.1% (range 0-41%) to completion of RT (mean 30 days) In 33 out of 34 pts there was a significant decrease in seroma vol during RT Average half-time of seroma was 15 days, and change followed an exponential decrease. RT was found to have minimal impact on change of seroma over the treatment course

Yue et al Med Phys 2013