Imaging for early stage breast cancer

Trial design: Inclusion Criteria Patient inclusio criteria and randomisation

• Breast conservation surgery ± adjuvant systemic therapy • Age ≥50, female

• Pathological tumour size ≤3cm • Invasive unifocal adenocarcinoma • Grade I, II or III • pN0 or pN1 • Minimum microscopic margin ≥2mm

Randomised (1:1:1) N=2018

Partial N=670

Reduced N=674

Whole N=674

Coles et al, Lancet 2017