Imaging for early stage breast cancer

Dosimetric comparison between 3D-CRT and IMRT

3D-CRT

IMRT

p

(cm 3 )

V

287

185

<0.0001

ref

PTV_EVAL

D

(%)

105

103

<0.0001

max

D95 (%)

100

100

0.0759

CN

<0.0001

0.6

0.8

ipsilat_nontarget breast

V95 %)

< 0.0001

9

3

V50 (%)

< 0.0001

40

31

ipsilat_lung

< 0.0001

V10 (%)

13

32

0.0058

V30 (%)

4

5

contralat_breast

< 0.0001

D5 (%)

1

5

contralat_lung

< 0.0001

V5 (%)

0.1

9

heart (left sided lesion)

0.0203

V5 (%)

16

9

0.4094

D5 (%)

9

8

CN: conformity number ( ≈ COIN)

The IMRT provided better results in dose conformation and sparing the dose for the ipsilateral

breast . However, advantages of 3D-CRT were observed, especially in the low dose region .

Stelczer et al. ESTRO 33, EP-1572