Imaging for early stage breast cancer

Image guidance with different surrogates for lumpectomy cavity

27 patients with two CT scans , three CT registration methods

surface matching

bony structures clip positions

residual error

7 ± 2 mm 3 ± 2 mm 5 ± 2 mm

residual error = distance between the COMs of the cavity in the reference and second scans

clip registration provided better localization in 93% of cases compared to bony structures

surface matching improved cavity localization in 70% of cases compared to bony structures

Hasan et al. IJROBP 70:619-625. 2008