Imaging for early stage breast cancer

The role of 4D-CT in APBI

- 3D and 4D CT-based IMRT plans for 10 patients - delineations on MIP images from 4D-CT - comparison of target and OARs dosimetry

3D-CT 4D-CT

PTV

V95%

97

97

Heart

V3 (%)

5

5

Uninvold ips. breast

V15 (%)

31.1

31.5

Contralat breast

V1 (%)

1.0

1.1

Ipsilat lung

V10 (%)

10.7

11.3

Contralat lung

V5 (%)

0.11

0.5

Comparison of PTVs between 3D-CT and 4D-CT plans

No significant differences between PTV volumes, PTV coverage, OAR sparing and

centroid position were found when comparing 3D-CT and 4D-CT plans

Conventional 3D CT-based planning is adequate for APBI

Meattini al. Radiol Med 120:1078-1082. 2015