Imaging for early stage breast cancer

Results and conclusions

3D-CRT (FB) %

3D-CRT (DIBH) %

IMRT (DIBH) %

PTV - V95

99.6

99.1

99.2

Ipsilat. non-PTV breast V50

42.7

39.4*

37.2*

Lung – V20

4.1

1.7*

1.4*

Lung - V10

9.2

4.6*

4.0*

Heart – max

8.2

4.8

3.8

Heart – mean

0.5

0.4*

0.5

LAD artery - max

6.1

2.2

1.8

LAD artery – mean

1.9

0.7

0.8

LAD: left anterior descending artery, * p < 0.05

- PTV coverage is acceptable with all three techniques - DIBH resulted in marked reduction in normal tissue dose compared with FB - IMRT showed further reduction in dose to OARs compared to 3D-CRT

Moran et al. IJROBP 75:294-301. 2009