In-room imaging and MR planning

Two Compartments Models Deconvolution

Deconcolving the tissue TAC with the arterial input function, would result in a BF-scaled IRF:

BF

t

There are different ways to perform the deconvolution step, and different assumptions that can be made to model the obtained IRF and to calculate different parameters.

Fieselman et al: “Deconvolution-Based CT and MR Brain Perfusion Measurement: Theoretical Model Revisited and Practical Implementation Details”, International Journal of Biomedical Images (2011).