Lower GI 2016

Prognostic Relevance of Apoptosis-related Markers

Results

Author Patients (n) Marker

58

Wong

p53

reduced local control and DFS

Bcl2: improved local control and DFS M30: reduced local control and DFS

98

Allal

Bcl2, M30

30

Ajani

NF- κ

B reduced DFS

62

Fraunholz

Survivin reduced DMFS and OS

improved local and distant control, CSS and OS

95

Rödel

pCaspase 8

Prognostic relevance of apoptosis-related markers still controversial

Rödel 2016 submitted; Fraunholz I, Radiat Oncol 2012, Allal AS, Clin Cancer Res 2003; Ajani JA, Dig Dis Sci 2010; Wong CS, Int J Radiat Oncol Biol Phys 1999