Lower GI 2016

Bone marrow

• RT-CT ≈ 60% Haematological Toxicity (HT)

• Dose constraints:

– Iliac crests: V50< 5%, V40 <35%, V30 < 50% (RTOG 0529 G3+ HT 57%)

• Bone marrow in the flat bones

≈ 50% in the pelvis

–

– Red BM (active); Yellow BM (inactive)

Kachnich LA et al Int J Radiat Oncol Biol Phys 2012