Lower GI 2017

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Immune checkpoints

supports trials of immunotherapy (targeting immune checkpoints via anti CTLA4/PD1/PDL1 agents)

either in the metastatic setting or potentially combined with chemo-radiotherapy either in the concurrent or (neo) adjuvant setting (Illidge 2015)

Illidge, T. Turning radiotherapy into an effective systemic anti-cancer treatment in combination with immunotherapy. Clin Oncol (R Coll Radiol). 2015 Dec;27(12):696-9

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