Lower GI 2017

The Royal Marsden Conclusions restaging MRI – prognostic and predictive imaging biomarkers for DFS – Persistent ymrEMVI seen twice as frequently as ypEMVI and independent risk factor for poor DFS – mrTRG 1-2 has similar DFS and OS as pCR but seen 4 times more frequently than pCR (prospective randomised trial data) – mrTRG1-2 represents a population of patients highly likely to have no viable tumour hence suitable for MRI monitoring in deferral of surgery trial – Patients will be randomised to have an mrTRG defined treatment strategy in the TRIGGER trial – do please join us!