Lower GI 2017

TRG : local recurrence & survival

131 cT3/T4 rectal cancers resected after pre-op CRT ( polish trial ) median follow-up 4 years

No.

5 yr LR 5 yr distant metastasis

4 yr DFS

TRG 0

22

5 % 9 %

91 %*

TRG 1

40

9 % 34 % 67 %

TRG 2

40

16 % 35 % 54 %

TRG 3

29

26 % 47 % 47 %

( * P = 0.015 )

NO significant difference in LR, distant recurrence or 4 yr disease free survival between TRG 1, 2 and 3 !!!

( Bujko et al 2010 )