Lower GI 2017

For resectable cancers pre-Operative Radiotherapy There are 2 preoperative adiation regimens accepted as standard:

• Short course (5 X 5 Gy delivered over 1 week) with surgery performed ideally within the next 5 days

• conventionally fractionated chemoradiation 45-50.4Gy (25-30 fractions of 1.8 or 2 Gy over 5-6 weeks) with surgery performed 4 to 10 weeks after treatment completion.

• (Folkesson et al, JCO 23, 24: 5644 – 5650, Kapiteijn et al , NEJM, 345 (9), 638-646, 2001, David Sebag-Montefiore et al, Lancet. 2009 Mar 7;373(9666):811-20)