Lower GI 2017

Only 3 Randomised Trials

Publication

n Regimens in trial PCR in Control

PCR in Novel arm

RTOG 0012 J Clin Oncol 2006

106 PVI 5FU + 44.2Gy - 60Gy versus PVI 5FU + Irinotecan 50.4Gy -54Gy

26%

T3/T4

26%

Jakobsen IJROBP 2012

248 50.4Gy + UFT versus 50.4Gy + UFT+ Brachytherapy

18%

18%

Engineer IJCRD 2013

90

45Gy + Cape Versus 40Gy +20Gy RT alone

7%

11%