Lower GI 2017

• Radiotherapy is generally regarded as a cell death inducing technique.

• Radiation also induces inflammatory or anti- inflammatory reactions depending on dose and fractionation Reichl B, et al. DEGRO practical guidelines for radiotherapy of non-malignant disorders: Part I: physical principles,radiobiological mechanisms, and radiogenic risk. Strahlenther Onkol 2015;191(9):701-9.

Shahabi V, et al. Immune-priming of the tumor microenvironment by radiotherapy: rationale for combination with immunotherapy to improve anticancer efficacy. Am J Clin Oncol 2015;38(1):90-7.