Lower GI 2017

Sequential vs concomitant boosting

- Existence of a dose effect vs Major response/pCR….boosting GTV

- Seq. vs SIB: different radiobiology meaning - SIB with conventional or moderate hypo - IMRT better than 3DCRT - From the point of view of plan optimization: Concomitant boosting is more efficient: better control of the dose to OARs, better conformity index ansd dose homogeneity in PTVs

Engels 2013 46Gy/23fr, SIB 55.2Gy (no CHT)

03/01/13