Lower GI 2017

Pelvic OARs constraints: bone marrow

- Acute Hematological toxicity reported in RT+CHT for rectal ca; unclear the long-term impact - Evidence of dose-volume effects for the pelvic bone marrow in rectal and anal canal ca. with 3DCRT +CHT (Mell 2007) - Predictive models of hematological tox for rectal ca treated with 3DCRT/IMRT +CHT (Yang 2014, Wan 2015) - Not yet reported BM-sparing planning strategies for rectal cancer…..potential interplay with bowel/bladder sparing

Yang 2014