Lower GI 2017

ACCORD 12/0405-Prodige-Trial

RT 45 Gy Cape

RT 50 Gy CapeOx

P-value

Number of pts

293

291

ypT0/TRG 4 (%)

13.9

19.2

.09

▲

Grade 3/4 Tox

▼

Compliance to CRT

Gérard et al., J Clin Oncol 2010

.78 HR 0.92 .25 HR 0.86

Local Relapse @5y (%)

8.8

7.8

64.7 △ 4.3%

Disease-free Survival @ 5y (%)

60.4

Doyen J et al., ESTRO 2016