Lower GI 2017

CAO/ARO/AIO-04

RT 50.4 Gy 5-FU

RT 50.4 Gy 5-FU/+Ox

P-value

Number of pts

623

613

pCR (%)

13

17

.04

=/ ▲

Grade 3/4 Tox

=

Compliance to CRT

Rödel et al., Lancet Oncol 2012

Local Relapse after R0/1 @3y (%)

4.6

2.9

75.9 △ 4.7%

.03 HR 0.79

Disease-free Survival @ 3y (%)

71.2

Rödel et al., Lancet Oncol 2015

(full paper from similar PETACC-6 pending)