Lower GI 2017

CAO/ARO/AIO-Experimental Track Phase I/II: Inclusion of molecular-targeted therapy

T1

T8

T22 T29

Ox

T M E

RT Cap CET

CET-CAPOX-RT (n=45)

CAPOX-RT (n=95)

Complete TRG (%)

9

18

Intermediate TRG /%)

55

68

Poor TRG (%)

36

15

Biomarker Studies Grimminger PG. et al., Clin Cancer Res 2011 Hu-Lieskovan S. et al., Clin Cancer Res 2011

Rödel C. et al., Int J Radiat Oncol Biol Phys 2008 Weiss C. et al., Int J Radiat Oncol Biol Phys 2010 Fokas E., et al., Int J Radiat Oncol Biol Phys 2013