Lower GI 2017

Aristotle National UK Trial schema n=920

MRI < 1mm from mesorectal fascia

Identify potential pt at MDT

Eligibility Intended post-op chemo policy

Capecitabine CRT (45Gy)

Capecitabine Irinotecan CRT (45Gy)

Surgery

Surgery

Post-op policy

Post-op policy

Primary endpoint 2 year DFS

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