Lower GI 2017

Unicancer Prodige 23 NCT01804790

Staging :- cT3/T4 Evaluated by TRUS and/or MRI

Capecitabine 800mg/m2

depending on ypTNM and the center's choice

S

50 Gy CRT

N=460

mFolfirinox, 6 cycles then

depending on ypTNM and the center's choice

S

Capecitabine 800mg/m2

Then 50 Gy CRT

Primary end point- 3 Year DFS