Lower GI 2017

Unsolved questions

• Role of brachytherapy • Management of inguinal region • Type and scheme of CT • Optimizing RT delivery

RTOG 0529 • Prospectively assess the utility of DP-IMRT in reducing the acute morbidity of 5FU/MMC chemoradiation – Primary endpoint: reduction of grade 2+ GI and GU AEs by at least 15%. – Secondary endpoints: • Potential reduction of all AEs with DP-IMRT • The investigator’s ability to perform DP-IMRT within the radiation planning guidelines delineated

Kachnik, IJROBP 2013c

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