Modern Bt Techniques - Florence 2016

Seeds with 131 Cs Radioactive Isotope

• 131 Cs isotope was suggested for BRT use back in 1960s (Henschke & Lawrence 1965)

• Based on Invention made by Donald C. Lawrence in 1967

• Developed by IsoRay, Inc. (Richland, WA, USA)

• Received FDA 510(k) clearance in 2003

• In 2009 FDA clearance for head & neck, lung and other sites (Proxcelan™ 131 Cs Brachytherapy Seeds)