Modern Bt Techniques - Florence 2016

Chemoradiation + Brachy

RTOG 92-07 50 Gy EBT + 3 x 5 Gy HDR 4 x 5FU / CDDP Applicator diameter 4-6 mm, prescrption 10 mm CR 73% G3 acute Tox 58%, G4 late Tox 8% Gaspar et al., Int. J. Radiat. Oncol. Biol. Phys. 37; 593-599, 1997

60 Gy EBT + 2 x 5 Gy HDR 3 x 5FU / CDDP / MMC Applicator diameter 10-14 mm, prescription @ 5mm 3 + 5 y Survival: 27% and 18% G3-4 late Tox 11% Calais et al., Int. J. Radiat. Oncol.

Biol. Phys. 38; 769-775, 1997