Molecular Imaging 2017

FDG PET/CT guided Dose Painting by Contours in HNC

Madani et al, IJROBP 2007 • n=41 patients • Phase I study • 2 different dose levels:

in 10 fx

– Dose level I: 25 Gy (n=23) – Dose level II: 30 Gy (n=18) – 22 fx à 2.16 Gy

• 2 cases of dose-limiting toxicity at dose level I • 1 treatment related death (dose level II) • Manual GTV PET delineation