Molecular Imaging 2017

Spectro glio trial

• robust and reproducible technique for MR spectroscopy coregistration with planning CT. •  Dosimetric comparaison on 16 patients : • IMRT SIB technique 72 Gy compared with 3D conformal RT 60 Gy :

– better target coverage, – better index conformity – better conformation number – equivalent or better OARs sparing .

60,00%

60-Gy 3D-CRT

60-Gy IMRT

50,00%

Dose-volumes relative to normal brain (%volume)

72-Gy SIB-IMRT

40,00%

30,00%

20,00%

10,00%

0,00%

Ken et al, Radiation Oncology 2013

V18 (18 Gy)

V36 (36 Gy)

V50 (50Gy)

MR spectroscopic imaging for dose-painting

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