Molecular Imaging 2017
Optimal time for response assessment ?
SSP RC versus non RC à S26
SSP RC versus non RC à S11
HR = 0,21 ; IC
: 0,15-0,29 (p < 0,001)
HR = 0,71 ; IC
: 0,53-0,95 (p = 0,02)
95
95
100
100
83 %
80 %
80
80
72 %
60
60
40
40
45 %
SSP (%)
PR CR
SSP (%)
PR CR
20
20
0 1 2 3 4 5 6 7 8 9 10 0
0
Years 0 1 2 3 4 5 6 7 8 9 10
Years
Response assessment at W11 seemed too early : 60 % of patients considered with partial response at S11 were in complete remission at W26
ASCO ® 2012 - D ’ après Glynne-Jones R et al., abstr. 4004 actualisé
Except in the case of progression, it is necessary to wait until 4-6 months after the end of radiochemotherapy, before discussing a salvage surgery in case of residual tumor
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