Molecular Imaging 2017

Source-to-background algorithms

PET image

Line profile

I

source

T = C·I

+ I

source

bg

signal intensity

I

bg

position

• Constant C determined from phantom measurements • Works very well for quasi-spherical lesions • Value of C depending of different factors: • Lesion size and shape • Scanner type and calibration Schaefer et al, EJNMMI 2008; 35(11): 1989-99.

• Reconstruction protocol • Image analysis software