Molecular Imaging 2017

Identification of a MRI perfusion biomarker to anticipate progression of glioblastoma after radio-chemotherapy

• 25 patients of spectro glio trial , follow up > 6 months • Analysis of 11 perfusion biomarkers

• The fraction of hypoperfused tumoral volume ≥ 0.61 could anticipate relapse at the following scan with sensibility/specificity of 92.3%/63.6%

• In the group >0,61 , 75% relapses vs 12.5%, p = 0.008.

Khalifa et al, Eur J Radiology 2016