Molecular Imaging 2017

Challenges for Diagnosis & Characterisation

Serum PSA:  15-30% men with

Systematic biopsies:  Miss up to 20-30% of cancers  Underestimates tumour aggressiveness in >20- 30% of cases

prostate cancer have normal PSA

 Abnormal PSA ≠ cancer: 7 of 10 no cancer present

Distinguishing aggressive (Rx: Definitive treatment) from indolent tumours (Rx: Surveillance) remains a challenge