Palliative care 2016
The Patchell-Study
randomized trial, stopped after interim analysis (Patchell, Lancet,
2005)
surgery plus 10 x 3 Gy (N=50) vs. 10 x 3 Gy alone
(N=51)
ability to walk after treatment: 42/50 (84%) vs. 29/51 (57%), p=0.001
maintaining ambulatory status for: median 122 vs. 13 days, p=0.003 Surgery only for selected patients (10-15%): KPS 70 , OS 3 mos., no paraplegia > 48 hrs., 1 spinal segment, no myeloma
• 10 years to accrue (not all eligible patients included?) • 10% more ambulatory patients than in other series • small number of patients (statistical power?)
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