Palliative care 2016
Phase II or retrospec+ve cohorts
Author; year
Design
Pts
Dose/frx
m-‐FU
Local control 2-‐years (%)
Survival 1-‐, 2-‐ years (%)
Mendez-‐ Romero 2006
Phase I/II
17
3x10-‐12.5 Gy
13 mts
86
85, 62
Rusthoven 2009 Phase I/II
47
3x12-‐20 Gy
16 mts
92
77, 30
Lee 2009
Phase I
68
6x4.6-‐10 Gy
11 mts
71 (1-‐yr)
79, 41 (3 yr.)
Goodman 2010
Phase I
19
1x18-‐30 Gy
17 mts
75
62, 49
3x10 Gy, 5x10 Gy, 5x12 Gy
56 89 100
90, 50 78, 67 75, 56
Rule 2010
Phase I
27
20 mts
Chang 2011 Liver mets: Local control rates 80-‐100% Retrospect 65 2-‐3x20 Gy 55 38 (2-‐yr) 77,45
Scorsei 2013
Phase II
61
3x25 Gy
12
91
83,38
4x12 – 3x25 Gy
Comito 2014
Phase II
42
24
80
80, 65
DeVin 2014
Retrospect
77
10x4-‐5 Gy
12
33
32 (3-‐yr)
Fode
Retrospect
225
3x15-‐22.5
29
LR: 13
80, 58
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