Palliative care 2016

Prognos+c factors related to survival aoer SBRT for mCRC

Covariate

Categories (n)

Median OS years (95 % CI) 2.5 (2.1 – 2.8) 1.2 (0.3-­‐ 1.9) 3.0 (2.4-­‐3.6) 3.5 (2.8-­‐4.2) 3.2 (2.6-­‐3.8) 2.9 (2.6-­‐3.6) 2.8 (2.5 – 3.4 ) 1.9 (1.5 – 2.1) 2.8 (2.3 – 3.4) 2.0 (1.8 – 2.5) 3.4 (2.3 – 5.1 ) 2.1 ( 1.9– 2.6) 2.6 (2.0 – 3.2) 2.1 (1.3 – 2.5) 2.6 (2.0-­‐ 2.8) 2.1 (1.9-­‐ 2.8) 2.5 (2.0 – 3.3) 2.3 (1.8 – 2.7)

HR

P-­‐ value

0-­‐1 (187) 2-­‐3 (14)

Performance status

2.54

<0.01

Males (136) Females (65)

Gender

0.65

0.03

<71 (101) >72 (100)

Age

1.10

0.38

≤ 30 mm (102) >30 mm (98)

Size of largest metastases

1.67

<0.01

1 metastasis (86) 2-­‐6 metastases (115)

Number of metastases

1.49

0.02

Lung (30) Liver, other (171)

Treatment site

1.74

0.03

Yes (132) No (69) Yes (98) No (103)

Prior chemotherapy

1.44

0.03

Prior local therapy

1.16

0.39

Metachronous (70) Synchronous (131)

Timing of metastasis

1.14

0.48