Palliative care 2017

Tramadol

• Weak opioid agonist • Acts on noradrenaline and 5HT uptake in spinal cord

• Single dose efficacy 150mg = 60mg codeine

• Chronic use = codeine • Similar side -effect profile to codeine/DHC  ?less constipating  NB epileptogenic with phenothiazines

• Max dose 100mg 6hrly = morphine 10mg 4 hourly