Particle Therapy 2017

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not circumferenPal

Small Bowel: Dose / Volume distribution in 31 patientsxx treated to mean target doses of 72.3 Gy(RBE) (range: 64-76) Volume mean (cc) range (cc) V 5 (24 pts.) 86.5 2.0 - 238 V20 (24 pts.) 45.1 0.2 - 151 V30 (22 pts.) 35.5 0.1 - 120 V40 (20 pts.) 27.5 0.2 - 89.0 V50 (19 pts.) 17.7 0.2 - 59.0 V60 (17 pts.) 7.6 0.4 - 29.0 V70 (12 pts.) 2.4 0.1 - 11.0 Volume mean (cc) range (cc) V75 (10 pts.) 1.9 <0.1 - 3.1 V80 (4 pts.) 0.2 <0.1 - 0.5 Using the sharp dose fall-off, proton therapy can deliver high doses to posterior bowel walls, yet only moderate doses to anterior bowel walls

Results at PSI

(Schneider et al., 2010, ASTRO presentation)

Small bowel can tolerate well doses > 60 Gy(RBE), as long as

XX = volume definition and analysis based on initial planning CT