Particle Therapy 2017

0 RADCOMP

Definitive reirradiation for locoregionally recurrent non-small cell lung cancer with proton beam therapy or intensity modulated radiation therapy: predictors of high-grade toxicity and survival outcomes. McAvoy S1

CONSORTIUM ➢ Considered strong indication. ➢ Multiple trials ongoing ➢ Issue: “cumulative dose of normal tissue” – how to deal with prior dose 1 year or 20 years ago (OAR dose constraint definition) ➢ Issue: Appropriate patient selection –i.e. who will benefit considering the risks? Example: Int J Radiat Oncol Biol Phys. 2014 Nov 15;90(4):819-27.

Re-irradiation: